Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL15323198 | 0.98 | GPR84 (0.41) | GPR84FFAR1TET2KDM4AKDM4C | |
| Deaminohydroxyvaline SCHEMBL15324660 | 0.84 | GPR84 (0.31) | GPR84FFAR1 | |
| Deaminohydroxyvaline SCHEMBL15324671 | 0.84 | GPR84 (0.40) | GPR84FFAR1TET2KDM4AKDM4C | |
| Malonic Acid SCHEMBL15322924 | 0.82 | LMNA (0.41) | OR51E2LDHASRR | |
| Malonic Acid SCHEMBL15323828 | 0.82 | LMNA (0.45) | OR51E2LDHASRR | |
| Deaminohydroxyvaline SCHEMBL15324291 | 0.79 | GPR84 (0.33) | GPR84FFAR1TET2KDM4AKDM4C | |
| Malonic Acid SCHEMBL15323090 | 0.77 | LDHA (0.36) | OR51E2LDHASRR | |
| Succinic Acid SCHEMBL15323337 | 0.77 | EGLN1 (0.36) | FFAR1TET2KDM4AKDM4CKDM2A | |
| Succinic Acid SCHEMBL15323882 | 0.76 | EGLN1 (0.39) | TET2KDM4AKDM4CKDM2ATET3 | |
| Deaminohydroxyvaline SCHEMBL15323262 | 0.76 | PDE4A (0.34) | OR51E2LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |