Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24587257 | 0.84 | ALPI (0.47) | MMP2ALPIPKMPTGS1XIAP | |
| SCHEMBL1537320 | 0.81 | ALPI (0.53) | MMP2ALPIPKMPTGS1XIAP | |
| SCHEMBL22689095 | 0.80 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL24586257 | 0.80 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1537425 | 0.77 | MMP2 (0.58) | MMP2ALPIPKMPTGS1XIAP | |
| SCHEMBL237821 | 0.77 | MMP2 (0.58) | MMP2ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL15323613 | 0.76 | SLC7A5 (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL15323367 | 0.75 | TLR2 (0.35) | TLR2 | |
| SCHEMBL4622400 | 0.75 | LTA4H (0.52) | MMP2ANPEPLTA4HSLC15A1SLC1A3 | |
| SCHEMBL20335061 | 0.75 | LTA4H (0.52) | MMP2ANPEPLTA4HSLC15A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |