Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.35 |
| ▸ | MARS1 | P56192 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323181 | 0.79 | MARS1 (0.33) | TLR2MARS1 | |
| SCHEMBL5586890 | 0.78 | GSR (0.40) | MARS1GSR | |
| SCHEMBL15323800 | 0.75 | SLC7A5 (0.33) | TLR2ALDH1A1LMNAGSR | |
| SCHEMBL15324153 | 0.75 | MMP2 (0.44) | TLR2 | |
| Methyl Alcohol SCHEMBL15322375 | 0.75 | PRKCA (0.38) | TLR2MARS1 | |
| SCHEMBL1345094 | 0.74 | GSR (0.47) | MARS1GSR | |
| SCHEMBL2319973 | 0.74 | METAP2 (0.36) | MARS1 | |
| SCHEMBL23766628 | 0.74 | GSR (0.50) | TLR2GSR | |
| Acrylic Acid SCHEMBL3102412 | 0.73 | MARS1 (0.35) | MARS1 | |
| SCHEMBL6574895 | 0.73 | GSR (0.46) | MARS1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |