Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 4/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727562 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL3728217 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL3728214 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL15323883 | 0.76 | SLC7A5 (0.34) | ALDH1A1LMNAPRKCA | |
| SCHEMBL1405394 | 0.75 | LMNA (0.56) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL3733637 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNATLR2PRKCAPRKCE | |
| SCHEMBL19300983 | 0.74 | PRKCA (0.47) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL25276653 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Threonine SCHEMBL15323039 | 0.73 | P2RY10 (0.40) | — | |
| Threonine SCHEMBL15324163 | 0.73 | P2RY10 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |