Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160037 | 0.85 | ALDH1A1 (0.56) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9386246 | 0.81 | SMN1; SMN2 (0.47) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL17113270 | 0.77 | MEN1 (0.52) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9867268 | 0.76 | KDM4E (0.43) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31160082 | 0.75 | HSD17B10 (0.44) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL28947282 | 0.75 | KDM4E (0.54) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL1279441 | 0.74 | KDM4E (0.66) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19124972 | 0.74 | KDM4E (0.53) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL3797257 | 0.72 | HPGD (0.47) | HPGDMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL15968932 | 0.72 | PLK1 (0.42) | HPGDMEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |