Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714988 | 0.88 | TARBP2 (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL19124972 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1PLK1MEN1KMT2A | |
| SCHEMBL24104598 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31115471 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1279441 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9716376 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1PLK1MEN1KMT2A | |
| SCHEMBL15324691 | 0.75 | HPGD (0.45) | KDM4EALDH1A1PLK1MEN1KMT2A | |
| SCHEMBL24105133 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1PLK1MEN1KMT2A | |
| SCHEMBL13315474 | 0.74 | ALDH1A1 (0.54) | KDM4EALDH1A1PLK1MEN1KMT2A | |
| SCHEMBL13315467 | 0.73 | ALDH1A1 (0.47) | KDM4EALDH1A1PLK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697994-A | Fused quinazoline derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-02-03 | — | — | CN | disclosed |