Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858499 | 0.84 | KDM4E (0.58) | ALDH1A1TSHRKDM4EATMPOLB | |
| SCHEMBL8144263 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL42787 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL29387332 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL8116309 | 0.83 | ALDH1A1 (0.66) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL6318035 | 0.83 | KDM4E (0.70) | ALDH1A1TSHRKDM4EATMPOLB | |
| SCHEMBL27494884 | 0.83 | ALDH1A1 (0.96) | ALDH1A1TSHRKDM4EATMADRA1D | |
| Ammonia Solution, Strong SCHEMBL28046886 | 0.83 | ALDH1A1 (0.96) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL27345462 | 0.83 | ALDH1A1 (0.96) | ALDH1A1TSHRKDM4EATMADRA1D | |
| SCHEMBL619175 | 0.81 | TSHR (0.69) | ALDH1A1TSHRKDM4EATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106537149-A | Method for screening trp channels | 宝洁公司 | 2017-03-22 | — | — | CN | claimed |
| EP-3126831-A1 | METHOD FOR SCREENING TRP CHANNELS | The Procter & Gamble Company (US) | 2017-02-08 | — | — | EP | claimed |
| WO-2015153184-A1 | METHOD FOR SCREENING TRP CHANNELS | THE PROCTER & GAMBLE COMPANY (US) | 2015-10-08 | — | — | WO | claimed |
| US-20150272907-A1 | Methods And Compositions For Modifying Sensorial Perception | THE PROCTER & GAMBLE COMPANY | 2015-10-01 | — | — | US | claimed |
| US-6369248-B1 | HYDROXY ESTERS FOR PERFUMES | GIVAUDAN SA (CH) | 2002-04-09 | — | — | US | claimed |
| US-6277889-B1 | FORMULATION CONTAINING ANTHRANILATE COMPOUND OR D-PULEGONE AS NONTOXIC ANIMAL REPELLENT AND METALDEHYDE | BOWEN IVOR (GB) | 2001-08-21 | — | — | US | claimed |
| EP-0989970-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-04-05 | — | — | EP | claimed |
| EP-0980863-A1 | Oxime carboxylic acid derivatives | Givaudan Roure (International) S.A. (CH) | 2000-02-23 | — | — | EP | claimed |
| WO-1998058899-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | WO | claimed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-2775839-B1 | METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | UNIV CALIFORNIA (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| US-11701305-B2 | Unit dose sachet comprising a perfume gel composition | Spritz, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-6251432-B1 | Sustained release dosage form unit having latex coating and method of making the same | ABBOTT LABORATORIES | 2001-06-26 | — | — | US | disclosed |
| WO-2001001966-A2 | SUSTAINED RELEASE DOSAGE FORM UNIT HAVING LATEX COATING AND METHOD OF MAKING THE SAME | ABBOTT LABORATORIES (US) | 2001-01-11 | — | — | WO | disclosed |
| EP-0989970-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-04-05 | — | — | EP | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0980863-A1 | Oxime carboxylic acid derivatives | Givaudan Roure (International) S.A. (CH) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998058899-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885TSHR 3246/4885KDM4E 3699/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885TSHR 3246/4885KDM4E 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.