Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.83 |
| ▸ | PRKCA | P17252 | 6/20 | 0.72 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076664 | 1.00 | ROCK2 (1.00) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL12570350 | 1.00 | ROCK2 (1.00) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL31691497 | 1.00 | ROCK2 (1.00) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL10017808 | 1.00 | ROCK2 (1.00) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL12570604 | 0.86 | PRKCA (0.81) | ROCK2PRKCQPRKCA | |
| SCHEMBL12570608 | 0.86 | PRKCQ (0.85) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL12570606 | 0.86 | PRKCQ (0.85) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL12570349 | 0.86 | PRKCQ (0.85) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL30885079 | 0.85 | PRKCQ (1.00) | ROCK2PRKCQPRKCAMAP3K5NTRK1 | |
| SCHEMBL18635718 | 0.83 | PRKCQ (0.79) | ROCK2PRKCQPRKCAMAP3K5NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169503-B2 | Method for producing indole derivative | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-27 | — | — | US | disclosed |
| US-20130273617-A1 | METHOD FOR PRODUCING INDOLE DERIVATIVE | UNIV NAT CHIAO TUNG (TW) | 2013-10-17 | — | — | US | disclosed |