SCHEMBL12570604

SCHEMBL12570604

C[C@@H]1O[C@@H](n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)C(=O)NC4=O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.81

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 7/20 0.81
▸ ROCK2 O75116 4/20 0.76
▸ PRKCQ Q04759 7/20 0.70
▸ CDK4 P11802 2/20 0.58
▸ CCND1 P24385 2/20 0.58
▸ TOP1 P11387 4/20 0.56
▸ PRKD3 O94806 3/20 0.56
▸ PRKCG P05129 3/20 0.56
▸ PRKCB P05771 3/20 0.56
▸ PRKCH P24723 3/20 0.56
▸ PRKCI P41743 3/20 0.56
▸ PRKCE Q02156 3/20 0.56
▸ PRKCZ Q05513 3/20 0.56
▸ PRKCD Q05655 3/20 0.56
▸ PRKD1 Q15139 3/20 0.56
▸ CCNE2 O96020 1/20 0.54
▸ CCNE1 P24864 1/20 0.54
▸ CDK2 P24941 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19050456 0.87 PRKCQ (0.68) PRKCAROCK2PRKCQCDK4CCND1
SCHEMBL5982059 0.87 PRKCA (0.80) PRKCATOP1
SCHEMBL10017808 0.86 ROCK2 (1.00) PRKCAROCK2PRKCQ
SCHEMBL12570350 0.86 ROCK2 (1.00) PRKCAROCK2PRKCQ
SCHEMBL15325110 0.86 ROCK2 (1.00) PRKCAROCK2PRKCQ
SCHEMBL31691497 0.86 ROCK2 (1.00) PRKCAROCK2PRKCQ
SCHEMBL30076664 0.86 ROCK2 (1.00) PRKCAROCK2PRKCQ
SCHEMBL12570605 0.84 PRKCQ (0.84) PRKCAROCK2PRKCQCDK4CCND1
SCHEMBL12570348 0.84 PRKCQ (0.84) PRKCAROCK2PRKCQCDK4CCND1
SCHEMBL12570607 0.84 PRKCQ (0.84) PRKCAROCK2PRKCQCDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3184537-B1 GLYCOSYLATED INDOLOCARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIV OVIEDO (ES) 2020-07-08 — — EP disclosed
EP-3184537-A1 GLYCOSYLATED INDOLOCARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF Universidad De Oviedo (ES) 2017-06-28 — — EP disclosed
EP-2277885-B1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIV OVIEDO (ES) 2017-03-15 — — EP disclosed
US-20110136753-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIVERSIDAD DE OVIEDO (ES) 2011-06-09 — — US disclosed
EP-2277885-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF Universidad De Oviedo (ES) 2011-01-26 — — EP disclosed
WO-2009125042-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF UNIVERSIDAD DE OVIEDO (ES) 2009-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136753-A1 GLYCOSYLATED INDOLECARBAZOLES, METHOD FOR OBTAINING SAME AND USES THEREOF PYGB, INMT, SI PRKCA 1688/4885ROCK2 315/4885PRKCQ 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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