Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16308854 | 0.82 | TDP1 (0.52) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL31285677 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL15004002 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL15137443 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL3172125 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL4725059 | 0.77 | NPC1 (0.61) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5084056 | 0.76 | MAPT (0.48) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL24105695 | 0.74 | ESR1 (0.48) | ALDH1A1SOS1CYP2C19 | |
| SCHEMBL15003942 | 0.74 | ALDH1A1 (0.82) | ALDH1A1TDP1GAAKDM4EL3MBTL1 | |
| SCHEMBL6687727 | 0.74 | ALDH1A1 (0.82) | ALDH1A1TDP1GAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150073165-A1 | CATALYST COMPOUNDS | THE UNIVIERSITY OF LIVERPOOL (GB) | 2015-03-12 | — | — | US | disclosed |
| WO-2013153408-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073165-A1 | CATALYST COMPOUNDS | NQO1, IDH2, IDH3B | ALDH1A1 115/4885TDP1 4332/4885GAA 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.