Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649226 | 0.78 | ESR1 (0.50) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2402249 | 0.76 | SLC6A4 (0.50) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15247632 | 0.76 | ESR1 (0.48) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15325823 | 0.74 | ALDH1A1 (0.63) | SOS1ALDH1A1CYP2C19 | |
| SCHEMBL6114378 | 0.74 | ESR1 (0.46) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28879943 | 0.74 | ESR1 (0.46) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9055270 | 0.71 | ALDH1A1 (0.55) | SLC6A4SLC6A2SLC6A3ADRA2ACYP2D6 | |
| SCHEMBL28682070 | 0.71 | ESR1 (0.54) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15854157 | 0.71 | ESR1 (0.54) | ESR1SOS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29061018 | 0.71 | ESR1 (0.54) | ESR1SLC6A4SLC6A2SLC6A3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877394-B1 | HYDROGENATION PROCESS OF OXIME DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-26 | — | — | EP | disclosed |
| US-20210387173-A1 | HYDROGENATION PROCESS OF OXIME DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387173-A1 | HYDROGENATION PROCESS OF OXIME DERIVATIVES | HMOX2, HAO2, PRDX5 | ESR1 3156/4885SOS1 2594/4885SLC6A4 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.