SCHEMBL1532680

SCHEMBL1532680

CC(C)(C)c1cc(-c2ccc(-c3ccc(-c4ccc(-c5cc(C(C)(C)C)c(-c6ccccc6)c(C(C)(C)C)c5)cc4)cc3)cc2)cc(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRB P28702 8/20 0.50
RXRA P19793 7/20 0.50
RXRG P48443 3/20 0.50
KIF11 P52732 3/20 0.40
EGFR P00533 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
DHODH Q02127 1/20 0.36
CYP2C9 P11712 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537452 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL76093 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL4309659 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL11331789 0.87 TSHR (0.44) RXRBRXRARXRGKIF11CYP2C9
SCHEMBL27757672 0.87 RXRB (0.62) RXRBRXRARXRGKIF11EGFR
SCHEMBL4572747 0.85 CA2 (0.39) RXRBRXRARXRGKIF11CA1
SCHEMBL11646120 0.84 RXRB (0.59) RXRBRXRARXRGKIF11EGFR
SCHEMBL30096028 0.82 RXRB (0.57) RXRBRXRARXRGKIF11EGFR
SCHEMBL4316640 0.81 RXRB (0.46) RXRBRXRARXRGKIF11EGFR
SCHEMBL5546207 0.80 RXRB (0.53) RXRBRXRARXRGKIF11EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6538725-B2 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2003-03-25 US claimed
US-20020135758-A1 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2002-09-26 US claimed
EP-3004234-B1 ILLUMINATING DEVICES WITH COLOR STABLE THERMOPLASTIC LIGHT-TRANSMITTING ARTICLES SABIC GLOBAL TECHNOLOGIES BV (NL) 2021-08-18 EP disclosed
EP-3004233-B1 COLOR STABLE THERMOPLASTIC COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-02-14 EP disclosed
US-9772086-B2 Illuminating devices with color stable thermoplastic light transmitting articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2017-09-26 US disclosed
US-9574083-B2 Synergistic effect of multiple mold release additives in polycarbonate based compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-21 US disclosed
US-9546269-B2 Transparent plastic article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-17 US disclosed
US-20150299460-A1 TRANSPARENT PLASTIC ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2015-10-22 US disclosed
US-20150240073-A1 SYNERGISTIC EFFECT OF MULTIPLE MOLD RELEASE ADDITIVES IN POLYCARBONATE BASED COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-08-27 US disclosed
EP-2888319-A1 TRANSPARENT PLASTIC ARTICLE SABIC Innovative Plastics IP B.V. (NL) 2015-07-01 EP disclosed
US-9006378-B2 Color stable thermoplastic composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-04-14 US disclosed
US-20050236481-A1 AUTHENTICATION SYSTEM, DATA DEVICE, AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2005-10-27 US disclosed
US-20050112768-A1 Method of authenticating tagged polymers CITIBANK, N.A., AS COLLATERAL AGENT 2005-05-26 US disclosed
US-20050109984-A1 Method of authenticating polymers, authenticatable polymers, methods of making authenticatable polymers and authenticatable articles, and articles made there from SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-05-26 US disclosed
US-20050109983-A1 Method of authenticating polymers, authenticatable polymers, methods of making authenticatable polymers and authenticatable articles, and articles made there from SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-05-26 US disclosed
US-20030038941-A1 Method for the rapid determination of the optical quality of combinatorial libraries GENERAL ELECTRIC COMPANY 2003-02-27 US disclosed
US-20030021998-A1 TAGGING MATERIALS FOR POLYMERS, METHODS, AND ARTICLES MADE THEREBY CITIBANK, N.A., AS COLLATERAL AGENT 2003-01-30 US disclosed
US-6499355-B1 Elongation and cracking testing and optical characterization of small-size coatings and materials GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed
US-6460417-B1 Formability testing of small-size coatings and materials GENERAL ELECTRIC COMPANY 2002-10-08 US disclosed
US-20020135758-A1 Method for determination of structural defects of coatings GENERAL ELECTRIC COMPANY 2002-09-26 US disclosed