SCHEMBL76093

SCHEMBL76093

CC(C)(C)c1cc(-c2cc(C(C)(C)C)c(-c3ccc(-c4ccc(-c5ccccc5)cc4)cc3)c(C(C)(C)C)c2)cc(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRB P28702 8/20 0.50
RXRA P19793 7/20 0.50
RXRG P48443 3/20 0.50
KIF11 P52732 3/20 0.40
EGFR P00533 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
DHODH Q02127 1/20 0.36
CYP2C9 P11712 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537452 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL1532680 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL4309659 1.00 RXRB (0.50) RXRBRXRARXRGKIF11EGFR
SCHEMBL11331789 0.87 TSHR (0.44) RXRBRXRARXRGKIF11CYP2C9
SCHEMBL27757672 0.87 RXRB (0.62) RXRBRXRARXRGKIF11EGFR
SCHEMBL4572747 0.85 CA2 (0.39) RXRBRXRARXRGKIF11CA1
SCHEMBL11646120 0.84 RXRB (0.59) RXRBRXRARXRGKIF11EGFR
SCHEMBL30096028 0.82 RXRB (0.57) RXRBRXRARXRGKIF11EGFR
SCHEMBL4316640 0.81 RXRB (0.46) RXRBRXRARXRGKIF11EGFR
SCHEMBL5546207 0.80 RXRB (0.53) RXRBRXRARXRGKIF11EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3362287-B1 MULTILAYER COATING WITH VISUAL EFFECT POLYNT COMPOSITES USA INC (US) 2022-07-20 EP disclosed
US-10450466-B2 Multilayer coating with visual effect Polynt Composites USA, Inc. (US) 2019-10-22 US disclosed
EP-3362287-A1 MULTILAYER COATING WITH VISUAL EFFECT Polynt Composites USA Inc. (US) 2018-08-22 EP disclosed
US-20170107377-A1 MULTILAYER COATING WITH VISUAL EFFECT Polynt Composites USA Inc. (NL) 2017-04-20 US disclosed
WO-2017066604-A1 MULTILAYER COATING WITH VISUAL EFFECT Polynt Composites USA, Inc. (US) 2017-04-20 WO disclosed
US-8129471-B2 Polycarbonate-poly(ether-ester) copolymer composition, method of manufacture, and articles therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-06 US disclosed
US-8114515-B2 Thermal reaction of such as 3,4-epoxycyclohexylmethyl-3,4-epoxycyclohexanecarboxylate with alkyl terephthalate homo or copolymer; adjusting conditions to tailor properties; injection molding materials; visually appealing construction materials and authentication documents SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-02-14 US disclosed
US-20110155975-A1 POLYCARBONATE-POLY(ETHER-ESTER) COPOLYMER COMPOSITION, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-30 US disclosed
US-20080185558-A1 CROSSLINKED POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND USES THEREOF GENERAL ELECTRIC COMPANY (US) 2008-08-07 US disclosed