Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.58 |
| ▸ | CTSS | P25774 | 16/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327336 | 0.93 | CTSS (0.50) | CTSLCTSSCTSK | |
| SCHEMBL696735 | 0.90 | CTSL (0.73) | CTSLCTSSCTSK | |
| SCHEMBL15327642 | 0.88 | CTSS (0.54) | CTSLCTSSCTSK | |
| SCHEMBL15327317 | 0.88 | CTSL (0.56) | CTSLCTSSCTSK | |
| SCHEMBL15327591 | 0.88 | CTSL (0.66) | CTSLCTSSCTSK | |
| SCHEMBL15327480 | 0.87 | CTSL (0.57) | CTSLCTSSCTSK | |
| SCHEMBL15327152 | 0.87 | CTSS (0.66) | CTSS | |
| SCHEMBL15327265 | 0.87 | CTSS (0.66) | CTSS | |
| SCHEMBL15327468 | 0.87 | CTSL (0.59) | CTSLCTSSCTSK | |
| SCHEMBL15327466 | 0.86 | CTSL (0.53) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |