Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684544 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HRH3KDM4EHPGDHTT | |
| SCHEMBL8436335 | 0.80 | MAPT (0.49) | ALDH1A1MAPTHRH3HPGDMMP2 | |
| SCHEMBL29508350 | 0.80 | TDP1 (0.61) | ALDH1A1MAPTKDM4E | |
| SCHEMBL10877536 | 0.80 | CYP2A6 (0.41) | ALDH1A1MAPTHRH3HPGDMAOB | |
| SCHEMBL10880690 | 0.80 | HRH3 (0.43) | ALDH1A1MAPTHRH3HPGDMMP2 | |
| SCHEMBL9450590 | 0.78 | TSHR (0.52) | ALDH1A1HRH3KDM4EHPGDHTT | |
| SCHEMBL9450589 | 0.78 | TSHR (0.52) | ALDH1A1HRH3KDM4EHPGDHTT | |
| SCHEMBL19962760 | 0.78 | TDP1 (0.61) | ALDH1A1MAPTHRH3HPGDHTT | |
| SCHEMBL16437754 | 0.76 | MMP2 (0.51) | ALDH1A1MAPTHRH3HPGDMMP2 | |
| SCHEMBL16437757 | 0.76 | MMP2 (0.51) | ALDH1A1MAPTHRH3HPGDMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | UNIVERSITY OF OREGON (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | HTT, ATXN2, SNRPD2 | ALDH1A1 3631/4885MAPT 1866/4885HRH3 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.