Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.56 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.56 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | S100B | P04271 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentamidine SCHEMBL9700132 | 0.78 | PRMT1 (0.80) | GAAPRMT1F2ST14PLAU | |
| Pentamidine Dao SCHEMBL548448 | 0.76 | PRMT1 (0.61) | GAAL3MBTL1PRMT1F2ST14 | |
| SCHEMBL321860 | 0.76 | LOXL2 (0.56) | F2ST14PLAUF10PLG | |
| SCHEMBL8410805 | 0.76 | HDAC3 (0.53) | GAAPRMT1F2ST14PLAU | |
| Pentamidine SCHEMBL21462086 | 0.75 | PRMT1 (0.75) | GAAPRMT1F2ST14PLAU | |
| SCHEMBL6956710 | 0.75 | TP53 (0.58) | GAAPRMT1F2ST14PLAU | |
| SCHEMBL14367306 | 0.75 | TP53 (0.54) | GAAL3MBTL1TP53TSHRSPHK1 | |
| SCHEMBL8045682 | 0.75 | PRMT1 (0.75) | PRMT1F2ST14PLAUPRMT5 | |
| SCHEMBL6957533 | 0.75 | TP53 (0.58) | GAAPRMT1F2ST14PLAU | |
| SCHEMBL752626 | 0.75 | TPMT (0.42) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | UNIVERSITY OF OREGON (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | UNIVERSITY OF OREGON (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | UNIVERSITY OF OREGON (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281462-A1 | ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY | HTT, ATXN2, SNRPD2 | GAA 462/4885L3MBTL1 35/4885PRMT1 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.