Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367487 | 0.83 | DRD2 (0.56) | KDM4E | |
| SCHEMBL16808253 | 0.81 | SLC2A1 (0.49) | TP53TSHRSMN1; SMN2PLA2G4BMMP1 | |
| SCHEMBL28472389 | 0.81 | TP53 (0.54) | TP53TSHRKDM4EHTTSMN1; SMN2 | |
| Acetic Acid SCHEMBL5624244 | 0.81 | KDM4E (0.57) | KDM4E | |
| SCHEMBL6407420 | 0.80 | MMP1 (0.56) | TP53TSHRKDM4ESMN1; SMN2PLA2G4B | |
| SCHEMBL14367305 | 0.80 | PLK1 (0.56) | TP53TSHRPLA2G4BGAAMMP1 | |
| SCHEMBL19486257 | 0.79 | ALDH1A1 (0.62) | TP53TSHRPLA2G4BMMP1RARB | |
| SCHEMBL28459280 | 0.79 | TP53 (0.59) | TP53TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL6960720 | 0.79 | GAA (0.54) | TP53TSHRGAA | |
| SCHEMBL1092185 | 0.78 | L3MBTL1 (0.85) | TP53TSHRSMN1; SMN2L3MBTL1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |