Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3739307 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL15329282 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5003928 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3808874 | 0.80 | PLK4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL16393478 | 0.80 | PDK2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5599726 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6234366 | 0.79 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL968897 | 0.79 | FAAH (0.31) | — | |
| Hydrochloric Acid SCHEMBL3378755 | 0.79 | FAAH (0.31) | — | |
| Hydrochloric Acid SCHEMBL29710455 | 0.79 | FAAH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013158411-A1 | METHODS OF SEPARATING COMPOUNDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-24 | — | — | WO | disclosed |
| US-20130276519-A1 | Methods of Separating Compounds | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-10-24 | — | — | US | disclosed |