Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560556 | 1.00 | ALDH1A1 (0.35) | ALDH1A1FDPSALDH1A3ALDH3A1TSHR | |
| SCHEMBL15330705 | 0.87 | IRAK4 (0.34) | ALDH1A1FDPSALDH1A3ALDH3A1 | |
| SCHEMBL15330394 | 0.87 | IRAK4 (0.34) | ALDH1A1FDPSALDH1A3ALDH3A1 | |
| SCHEMBL2560016 | 0.85 | FDPS (0.30) | FDPS | |
| SCHEMBL15332272 | 0.85 | FDPS (0.30) | FDPS | |
| SCHEMBL2559960 | 0.84 | CA2 (0.34) | ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL15329939 | 0.84 | CA2 (0.34) | ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL2558546 | 0.83 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL2560998 | 0.83 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL2554581 | 0.81 | TYR (0.35) | ALDH1A1FDPSALDH1A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |