Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852871 | 0.93 | ALOX5 (0.53) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13600434 | 0.89 | ALOX5 (0.57) | ALOX5MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL232779 | 0.85 | TP53 (0.64) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL11692409 | 0.84 | GAA (0.50) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| Acetone SCHEMBL28637824 | 0.83 | TP53 (0.58) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL2367399 | 0.83 | HTT (0.63) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9133420 | 0.83 | TP53 (0.62) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2299193 | 0.83 | TP53 (0.62) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3088495 | 0.83 | TP53 (0.62) | ALOX5TP53MEN1KMT2AALDH1A1 | |
| Methane SCHEMBL7896214 | 0.83 | TP53 (0.62) | ALOX5TP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051281-B2 | Compounds | GLAXOSMITHKLINE LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-20130281499-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281499-A1 | COMPOUNDS | CYP11B2, SCD, CYP11B1 | ALOX5 190/4885TP53 4714/4885MEN1 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.