Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823330 | 1.00 | CES2 (0.42) | CES2IDO1GPR35ADRB1TSHR | |
| SCHEMBL10271930 | 1.00 | CES2 (0.42) | CES2IDO1GPR35ADRB1TSHR | |
| SCHEMBL383565 | 0.97 | CES2 (0.44) | CES2IDO1GPR35ADRB1TSHR | |
| SCHEMBL16861287 | 0.94 | CES2 (0.42) | CES2IDO1GPR35ADRB1TSHR | |
| SCHEMBL26212657 | 0.85 | RAPGEF4 (0.46) | CES2IDO1MAPTRAPGEF4RXRA | |
| SCHEMBL15338946 | 0.85 | RAPGEF4 (0.46) | CES2IDO1MAPTRAPGEF4RXRA | |
| SCHEMBL16145497 | 0.84 | CYP3A4 (0.52) | IDO1TSHRALDH1A1MAPTRXRA | |
| SCHEMBL6251039 | 0.79 | TSHR (0.42) | CES2IDO1TSHRALDH1A1MAPK1 | |
| SCHEMBL440959 | 0.78 | CES2 (0.58) | CES2IDO1GPR35ADRB1TSHR | |
| SCHEMBL7798387 | 0.76 | CES2 (0.46) | CES2IDO1GPR35ADRB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793504-B2 | Methods for cross coupling | RECURIUM IP HOLDINGS, LLC (US) | 2020-10-06 | — | — | US | claimed |
| US-20190202769-A1 | METHODS FOR CROSS COUPLING | RECURIUM IP HOLDINGS, LLC | 2019-07-04 | — | — | US | claimed |
| EP-3504217-A1 | METHODS FOR CROSS COUPLING | Zeno Royalties & Milestones, LLC (US) | 2019-07-03 | — | — | EP | claimed |
| WO-2018039232-A1 | METHODS FOR CROSS COUPLING | KALYRA PHARMACEUTICALS, INC. (US) | 2018-03-01 | — | — | WO | claimed |
| US-9056314-B2 | Palladium catalyst, method for its preparation and its use | H4SEP KFT (HU) | 2015-06-16 | — | — | US | claimed |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | CHINOIN GYOGYSZER-ES VEGYESZETI TER-MEKEK GYARA ZRT (HU) | 2013-10-24 | — | — | US | claimed |
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-112638985-B | Fluorine-containing aromatic polymer and method for producing same | 大金工业株式会社 | 2024-03-15 | — | — | CN | disclosed |
| US-20230097871-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20230069963-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2023-03-09 | — | — | US | disclosed |
| EP-4008405-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2022-06-08 | — | — | EP | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |
| EP-2886545-B1 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2016-06-29 | — | — | EP | disclosed |
| WO-2016066241-A1 | PROCESS FOR PREPARING THIADIAZOLO-ISOINDOLE-DIONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-05-06 | — | — | WO | disclosed |
| EP-2886545-A1 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2015-06-24 | — | — | EP | disclosed |
| US-9056314-B2 | Palladium catalyst, method for its preparation and its use | H4SEP KFT (HU) | 2015-06-16 | — | — | US | disclosed |
| US-9056314-B2 | Palladium catalyst, method for its preparation and its use | H4SEP KFT (HU) | 2015-06-16 | — | — | US | disclosed |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | CHINOIN GYOGYSZER-ES VEGYESZETI TER-MEKEK GYARA ZRT (HU) | 2013-10-24 | — | — | US | disclosed |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | CHINOIN GYOGYSZER-ES VEGYESZETI TER-MEKEK GYARA ZRT (HU) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230097871-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | LPAR1, LPAR2, LPAR3 | CES2 3066/4885IDO1 1574/4885GPR35 139/4885 |
| US-20190202769-A1 | METHODS FOR CROSS COUPLING | F2, C5, C9 | CES2 1228/4885IDO1 167/4885GPR35 4410/4885 |
| US-20230069963-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | ZC3HAV1, ZC3HAV1L, IL5 | CES2 4883/4885IDO1 2757/4885GPR35 1195/4885 |
| US-20130281700-A1 | PALLADIUM CATALYST, METHOD FOR ITS PREPARATION AND ITS USE | PDS5A, DDT, PDS5B | CES2 2917/4885IDO1 208/4885GPR35 1922/4885 |
| US-10793504-B2 | Methods for cross coupling | F2, C5, C9 | CES2 1228/4885IDO1 167/4885GPR35 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.