Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383565 | 0.78 | CES2 (0.44) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL7795645 | 0.77 | CES2 (0.48) | CES2IDO1MAPTALDH1A1TSHR | |
| SCHEMBL440959 | 0.76 | CES2 (0.58) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL16861287 | 0.76 | CES2 (0.42) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL15329899 | 0.76 | CES2 (0.42) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL2879502 | 0.74 | CES2 (0.41) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL497733 | 0.74 | CES2 (0.41) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL2227681 | 0.74 | CES2 (0.41) | CES2IDO1RXRARXRBRXRG | |
| SCHEMBL7526444 | 0.74 | CES2 (0.46) | CES2ALDH1A1TSHR | |
| SCHEMBL1305235 | 0.74 | GABRA1 (0.46) | RXRARXRBRXRGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10072033-B2 | N-(phosphinoalkyl)-N-(thioalkyl)amine derivative, method for producing same, and metal complex thereof | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2018-09-11 | — | — | US | disclosed |
| US-20170233418-A1 | N-(PHOSPHINOALKYL)-N-(THIOALKYL)AMINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METAL COMPLEX THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5621129-A | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5484902-A | HYDROCYANATION OF VINYL AROMATICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5312957-A | 2-/6-Methoxy-2-naphthalene/propionitrile | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5175335-A | Reacting vinyl aryl compounds with a source of hydrocyanic acid in presence of nickle zero valent compound and nonracemic bidentate organophosphorus ligand | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233418-A1 | N-(PHOSPHINOALKYL)-N-(THIOALKYL)AMINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METAL COMPLEX THEREOF | NSFL1C, TST, NCL | CES2 2520/4885IDO1 2171/4885RXRA 4650/4885 |
| US-10072033-B2 | N-(phosphinoalkyl)-N-(thioalkyl)amine derivative, method for producing same, and metal complex thereof | NSFL1C, TST, NCL | CES2 2520/4885IDO1 2171/4885RXRA 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.