Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330513 | 0.80 | ALDH1A1 (0.49) | KDM4EHSD17B10SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL15331597 | 0.79 | EPHX2 (0.60) | KDM4EHTTALDH1A1LMNATSHR | |
| SCHEMBL15331059 | 0.79 | SMN1; SMN2 (0.66) | KDM4EUSP2ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL15332590 | 0.78 | KDM4E (0.67) | KDM4EUSP2ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL15333129 | 0.75 | ADRA2B (0.50) | SMN1; SMN2HTTRAB9AALDH1A1NPC1 | |
| SCHEMBL10282918 | 0.75 | SMN1; SMN2 (0.70) | KDM4EUSP2ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL2558894 | 0.75 | ALDH1A1 (0.52) | KDM4ESMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL15331221 | 0.74 | ALDH1A1 (0.59) | KDM4EUSP2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15332251 | 0.74 | LMNA (0.49) | KDM4EUSP2HSD17B10SMN1; SMN2HTT | |
| SCHEMBL15333076 | 0.73 | LMNA (0.41) | KDM4EHSD17B10SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |