Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173028 | 0.81 | ALDH1A1 (0.56) | NLRP3ENPP2SMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL519364 | 0.79 | NLRP3 (0.45) | NLRP3SMN1; SMN2LMNABRD4 | |
| SCHEMBL18412742 | 0.78 | ALDH1A1 (0.51) | KDM1ABRPF1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23191109 | 0.78 | ENPP2 (0.42) | TRPV1NLRP3ENPP2ALDH1A1KDM4E | |
| SCHEMBL20963122 | 0.78 | HSD17B2 (0.54) | KDM1ANLRP3BRPF1MAP1LC3BMAP1LC3A | |
| SCHEMBL6666 | 0.77 | HTT (0.59) | TRPV1NLRP3SMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL29955257 | 0.77 | HTT (0.59) | TRPV1NLRP3SMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL13468554 | 0.76 | HPGD (0.51) | KDM1ABRPF1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL519912 | 0.75 | AURKA (0.48) | NLRP3MAP1LC3BSMN1; SMN2BRD4 | |
| SCHEMBL22222881 | 0.75 | KDM1A (0.48) | KDM1ABRPF1MAP1LC3BMAP1LC3ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |