SCHEMBL15330706

SCHEMBL15330706

Cc1nn(C)c(Cl)c1CN1CCCCC1C=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.46
ATM Q13315 1/20 0.46
ALDH1A1 P00352 5/20 0.42
POLB P06746 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
FPR2 P25090 3/20 0.33
PROKR1 Q8TCW9 3/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330672 0.76 L3MBTL1 (0.47) L3MBTL1ATMALDH1A1POLBKMT2A
SCHEMBL15330289 0.74 L3MBTL1 (0.52) L3MBTL1ATMALDH1A1POLBKMT2A
SCHEMBL13038815 0.69 POLB (0.47) L3MBTL1ATMALDH1A1POLBKMT2A
SCHEMBL14375238 0.69 L3MBTL1 (0.51) L3MBTL1ATMALDH1A1POLBKMT2A
SCHEMBL6443378 0.67 ALDH1A1 (0.47) ALDH1A1KDM4E
SCHEMBL1300042 0.65 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1
SCHEMBL1299354 0.65 KCNK3 (0.39) POLBSMN1; SMN2LMNA
SCHEMBL15383931 0.64 ALDH1A1 (0.34) L3MBTL1ALDH1A1
SCHEMBL27541668 0.64 ALDH1A1 (0.34) L3MBTL1ALDH1A1
SCHEMBL27267849 0.64 OPRD1 (0.45) L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed