Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533774 | 0.93 | RARB (0.39) | RARBRARARARGMCL1CYP1A2 | |
| SCHEMBL1533758 | 0.90 | ESR1 (0.37) | RARBRARARARGESR1ESR2 | |
| SCHEMBL1533776 | 0.90 | RARB (0.42) | RARBRARARARGMCL1CYP1A2 | |
| SCHEMBL1533786 | 0.89 | RARB (0.36) | RARBRARARARGMCL1CYP1A2 | |
| SCHEMBL1533783 | 0.88 | RARB (0.47) | RARBRARARARGMCL1CYP1A2 | |
| SCHEMBL1533754 | 0.86 | RARB (0.40) | RARBRARARARGMCL1ESR1 | |
| SCHEMBL24300864 | 0.85 | RARB (0.34) | RARBRARARARGMCL1CYP1A2 | |
| SCHEMBL1533777 | 0.85 | RARB (0.39) | RARBRARARARGMCL1ESR1 | |
| SCHEMBL224532 | 0.85 | RARB (0.36) | RARBRARARARGMCL1NPC1 | |
| SCHEMBL24300869 | 0.84 | MAOA (0.34) | RARBRARARARGMCL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067879-A1 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| EP-2265692-B1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2012-07-04 | — | — | EP | disclosed |
| US-20110049427-A1 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20110049427-A1 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT (DE) | 2011-03-03 | — | — | US | disclosed |
| US-20110049427-A1 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT (DE) | 2011-03-03 | — | — | US | disclosed |
| EP-2265692-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | Merck Patent GmbH (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009129915-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009129915-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110049427-A1 | Thiophene derivatives, and LC media containing same | TPMT, TEC, LCT | RARB 3984/4885RARA 4056/4885RARG 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.