Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223390 | 0.93 | RARB (0.37) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL26566721 | 0.90 | MAOB (0.34) | RARBRARARARGGRIN2BMAOB | |
| SCHEMBL224331 | 0.90 | GRIN2B (0.34) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL221784 | 0.89 | RARB (0.34) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL22872121 | 0.86 | RARB (0.38) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL1533784 | 0.85 | RARB (0.39) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL27027365 | 0.85 | RARB (0.33) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL225979 | 0.84 | RAB9A (0.38) | RARBRARARARGMAPTNPC1 | |
| SCHEMBL26481762 | 0.84 | RARB (0.49) | RARBRARARARGMAPTRAB9A | |
| SCHEMBL26481759 | 0.83 | RARB (0.48) | RARBRARARARGMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067879-A1 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| WO-2023232753-A1 | FERROELECTRIC SMECTIC LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023198669-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198673-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198671-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-19 | — | — | WO | disclosed |
| EP-4261269-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20230323207-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| CN-107011920-B | Liquid-crystalline medium comprising thiophene derivatives | 默克专利股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| EP-3271440-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |
| EP-2598604-B1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| WO-2012013281-A1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013281-A1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012007096-A1 | LIQUID-CRYSTALLINE MEDIUM WITH STABILIZER | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007096-A1 | LIQUID-CRYSTALLINE MEDIUM WITH STABILIZER | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| EP-2398787-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | Merck Patent GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010099853-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010099853-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | TEC, TPMT, TST | RARB 3907/4885RARA 3956/4885RARG 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.