SCHEMBL15340283

SCHEMBL15340283

CCOc1ccc(C2CCC(c3ccc(-c4ccc(C)cc4)c(C)c3F)CO2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
HSD17B10 Q99714 2/20 0.33
XBP1 P17861 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.32
FPR2 P25090 3/20 0.31
SLC5A2 P31639 1/20 0.31
KDM1A O60341 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15340275 0.87 MAPT (0.34) MAPTKDM4ELMNAHPGDCASP1
SCHEMBL15340326 0.86 MAPT (0.36) MAPTFFAR4MEN1KMT2A
SCHEMBL15340288 0.82 KDM4E (0.32) MAPTKDM4EALDH1A1
SCHEMBL15340299 0.81 MEN1 (0.34) MAPTKDM4EHPGDALDH1A1MEN1
SCHEMBL15343912 0.80 CHRM2 (0.36) FFAR4FPR2NPC1RAB9A
SCHEMBL15343896 0.78 CHRM2 (0.36) FFAR4FPR2RAB9A
SCHEMBL15340312 0.78 FPR2 (0.36) MEN1KMT2AFPR2KDM1A
SCHEMBL15343897 0.78 FPR2 (0.31) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL15340281 0.77 ALOX5 (0.37)
SCHEMBL15340025 0.76 FPR2 (0.34) MEN1KMT2AFPR2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102871-B2 Liquid crystal compound showing negative dielectric anisotropy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-08-11 US disclosed
US-20130277610-A1 LIQUID CRYSTAL COMPOUND SHOWING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed