SCHEMBL15340326

SCHEMBL15340326

CCOc1ccc(C2CCC(c3ccc(COc4ccc(C)cc4)c(C)c3F)CO2)cc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
HTR6 P50406 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR4 Q5NUL3 1/20 0.31
CACNA2D1 P54289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15340283 0.86 MAPT (0.36) MAPTMEN1KMT2AFFAR4
SCHEMBL15340288 0.82 KDM4E (0.32) MAPT
SCHEMBL15340299 0.77 MEN1 (0.34) MAPTMEN1KMT2A
SCHEMBL15340275 0.77 MAPT (0.34) MAPTMEN1KMT2A
SCHEMBL15340025 0.76 FPR2 (0.34) MEN1KMT2A
SCHEMBL15340006 0.76 MAPT (0.31) MAPT
SCHEMBL15343735 0.75
SCHEMBL15340141 0.75 HTR6 (0.31) HTR6
SCHEMBL15343834 0.74 TP53 (0.30)
SCHEMBL15340312 0.74 FPR2 (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102871-B2 Liquid crystal compound showing negative dielectric anisotropy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-08-11 US disclosed
US-20130277610-A1 LIQUID CRYSTAL COMPOUND SHOWING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed