Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | JUN | P05412 | 2/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | CDC42 | P60953 | 1/20 | 0.45 |
| ▸ | RAC1 | P63000 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15340537 | 1.00 | HDAC1 (0.52) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340538 | 1.00 | HDAC1 (0.52) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15343965 | 0.91 | HDAC1 (0.58) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15343963 | 0.91 | HDAC1 (0.58) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15343964 | 0.91 | HDAC1 (0.58) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340502 | 0.85 | HDAC1 (0.53) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340503 | 0.85 | HDAC1 (0.53) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340504 | 0.85 | HDAC1 (0.53) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340526 | 0.83 | HDAC1 (0.49) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15340525 | 0.83 | HDAC1 (0.49) | HDAC1HDAC2HDAC8GSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | HSD17B14, SORD, GPX4 | HDAC1 2348/4885HDAC2 1662/4885HDAC8 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.