SCHEMBL15340797

SCHEMBL15340797

CCc1cc(N2CCOCC2)ccc1[N+](=O)[O-]

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 17/20 0.66
PKM P14618 1/20 0.66
LMNA P02545 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
HPGD P15428 1/20 0.62
ALDH1A1 P00352 9/20 0.62
MAPK1 P28482 3/20 0.62
NPSR1 Q6W5P4 2/20 0.61
CYP2C9 P11712 1/20 0.57
HTT P42858 2/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
KDM4E B2RXH2 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5054712 0.87 MAPT (0.68) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL16284337 0.85 HPGD (0.68) MAPTLMNASMN1; SMN2HPGDALDH1A1
SCHEMBL10061538 0.85 MAPT (0.61) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL16284338 0.84 SIRT6 (0.68) MAPTALDH1A1MAPK1L3MBTL1
SCHEMBL10061540 0.84 MAPT (0.60) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL17919917 0.84 MAPT (0.60) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL18036523 0.83 MAPT (0.75) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL443596 0.82 HPGD (0.73) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL29788558 0.82 HPGD (0.73) MAPTPKMLMNASMN1; SMN2HPGD
SCHEMBL22778043 0.81 MAPT (0.79) MAPTPKMLMNASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9832880-B2 Electronic apparatus and method for manufacturing the same Innolux Corporation (TW) 2017-11-28 US disclosed
US-9428508-B2 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as FAK/Pyk2 inhibitors CENTAURUS BIOPHARMA CO., LTD. (CN) 2016-08-30 US disclosed
US-20140362545-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME Innolux Corporation (TW) 2014-12-11 US disclosed
US-20140362545-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME Innolux Corporation (TW) 2014-12-11 US disclosed
US-20130281438-A1 2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS CENTAURUS BIOPHARMA CO., LTD. (CN) 2013-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281438-A1 2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS PTK2B, PTK2, DAPK2 MAPT 1164/4885PKM 652/4885LMNA 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.