Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469715 | 0.72 | PTGS2 (0.40) | PTGS2KDM4EPI4KBP2RY2CSNK2A2 | |
| Hydrochloric Acid SCHEMBL21229051 | 0.72 | PTGS2 (0.40) | PTGS2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL13610783 | 0.72 | SMN1; SMN2 (0.59) | PTGS2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL28800465 | 0.70 | MEN1 (0.55) | SMN1; SMN2NPC1RAB9ACDK2KMT2A | |
| SCHEMBL15943687 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2ALOX12MAPK10NPC1RAB9A | |
| SCHEMBL13436508 | 0.66 | CDK2 (0.55) | SMN1; SMN2P2RY2CCNE1CDK2CDK5 | |
| SCHEMBL21250386 | 0.66 | ALDH1A1 (0.40) | SMN1; SMN2CCNE1CDK2CDK5TMPRSS15 | |
| SCHEMBL25142670 | 0.65 | RAB9A (0.52) | SMN1; SMN2KDM4ENPC1RAB9ATP53 | |
| SCHEMBL6644838 | 0.65 | KMT2A (0.57) | SMN1; SMN2KDM4ENPC1RAB9APOLB | |
| SCHEMBL18667818 | 0.64 | ALDH1A1 (0.39) | SMN1; SMN2POLBCCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | PTGS2 3542/4885SMN1; SMN2 1081/4885ALOX12 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.