SCHEMBL15344249

SCHEMBL15344249

CCCCOc1c(CO)nn(C)c(=O)c1-c1c(CC)cc(C)cc1CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
IDO1 P14902 1/20 0.33
CRHR1 P34998 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.31
CCNE2 O96020 2/20 0.30
CCNE1 P24864 2/20 0.30
CDK2 P24941 2/20 0.30
CCNT1 O60563 1/20 0.30
CCNB2 O95067 1/20 0.30
CDK1 P06493 1/20 0.30
CDK4 P11802 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNA2 P20248 1/20 0.30
CCND1 P24385 1/20 0.30
CCND2 P30279 1/20 0.30
CCND3 P30281 1/20 0.30
CDK7 P50613 1/20 0.30
CDK9 P50750 1/20 0.30
CCNH P51946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15344163 0.90 SMN1; SMN2 (0.31) SMN1; SMN2CRHR1
SCHEMBL15344245 0.88 SMN1; SMN2 (0.32) SMN1; SMN2CCNE2CCNE1CDK2CCNT1
SCHEMBL15344241 0.88 CNR1 (0.34) SMN1; SMN2CRHR1LMNACCNE2CCNE1
SCHEMBL15344244 0.87
SCHEMBL15063888 0.85 KMT2A (0.32) CRHR1LMNACCNE2CCNE1CDK2
SCHEMBL15344235 0.85 GRM2 (0.31) SMN1; SMN2
SCHEMBL15344248 0.83 THRA (0.33) CRHR1LMNA
SCHEMBL15344236 0.83
SCHEMBL15344237 0.82 KAT2B (0.33) CRHR1
SCHEMBL15333651 0.82 PKM (0.39) SMN1; SMN2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029295-B2 Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-12 US disclosed
US-20130281299-A1 PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT SUMITOMO CHEMICAL COMPANY,LIMITED (JP) 2013-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281299-A1 PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT ACHE, CBR3, DDT SMN1; SMN2 2614/4885IDO1 542/4885CRHR1 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.