Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344558 | 0.91 | PPARA (0.53) | PPARAMCL1PPARGKAT8RARB | |
| SCHEMBL15344587 | 0.90 | PPARA (0.53) | PPARAALDH1A1PPARGKAT8MEN1 | |
| SCHEMBL3385017 | 0.89 | ALDH1A1 (0.52) | PPARAMCL1ALDH1A1PPARGKAT8 | |
| SCHEMBL15344555 | 0.87 | PPARA (0.53) | PPARAMCL1ALDH1A1PPARGKAT8 | |
| SCHEMBL27888037 | 0.87 | ALDH1A1 (0.50) | PPARAMCL1ALDH1A1PPARGMEN1 | |
| SCHEMBL27904900 | 0.87 | ALDH1A1 (0.50) | PPARAMCL1ALDH1A1PPARGMEN1 | |
| SCHEMBL11055698 | 0.87 | ALDH1A1 (0.50) | PPARAMCL1ALDH1A1PPARGMEN1 | |
| SCHEMBL9700198 | 0.87 | PPARA (0.61) | PPARAALDH1A1PPARGKAT8MEN1 | |
| SCHEMBL1927021 | 0.83 | HNF4A (0.55) | PPARAMCL1ALDH1A1TSHRPTPN1 | |
| SCHEMBL28542307 | 0.83 | PPARA (0.47) | PPARAALDH1A1PPARGKAT8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |