Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777600 | 0.79 | NPSR1 (0.53) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL27129568 | 0.76 | NPSR1 (0.50) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL3468257 | 0.76 | NPSR1 (0.50) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL18485606 | 0.76 | NPSR1 (0.50) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL124863 | 0.76 | NPSR1 (0.55) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL18485604 | 0.74 | NPSR1 (0.57) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL15279130 | 0.74 | NPSR1 (0.48) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL776404 | 0.73 | NPSR1 (0.52) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL1686093 | 0.73 | NPSR1 (0.52) | NPSR1VCPNPC1RAB9AHSP90AA1 | |
| SCHEMBL8103677 | 0.72 | NPSR1 (0.59) | NPSR1VCPNPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289104-A1 | ALIPHATIC AMINO ACID BIOSYNTHESIS INHIBITORS AND A METHOD OF SYNTHESIZING THE SAME | Sardari, Soroush (IR) | 2013-10-31 | — | — | US | disclosed |
| US-8569361-B1 | Aliphatic amino acid biosynthesis inhibitors and a method of synthesizing the same | SARDARI SOROUSH (IR) | 2013-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289104-A1 | ALIPHATIC AMINO ACID BIOSYNTHESIS INHIBITORS AND A METHOD OF SYNTHESIZING THE SAME | DDC, BCAT2, BCAT1 | NPSR1 4597/4885VCP 375/4885NPC1 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.