SCHEMBL15345381

SCHEMBL15345381

CCC1(CN)C=Cc2ccccc2C1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.37
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PARP1 P09874 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28699182 0.77 NPSR1 (0.36) HTR2AALDH1A1LMNATSHRNPSR1
SCHEMBL7159531 0.75 ALDH1A1 (0.37) ALDH1A1
SCHEMBL5290390 0.74 PARP1 (0.34) CA1CA2PARP1
SCHEMBL9532397 0.74 NPSR1 (0.37) HTR2AALDH1A1LMNATSHRNPSR1
SCHEMBL15345499 0.72 MAOB (0.40) HTR2ACA1CA2PARP1
SCHEMBL10339778 0.70 ALDH1A1 (0.40) ALDH1A1LMNATSHR
SCHEMBL1697644 0.70 PARP1 (0.36) HTR2AALDH1A1KMT2ACA1CA2
SCHEMBL258234 0.70 PARP1 (0.36) CA1CA2PARP1
SCHEMBL1725344 0.70 PARP1 (0.36) CA1CA2PARP1
SCHEMBL31520302 0.70 PARP1 (0.36) CA1CA2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657214-A1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL Mitsubishi Gas Chemical Company, Inc. (JP) 2013-10-30 EP disclosed