SCHEMBL15345499

SCHEMBL15345499

NCC1(c2ccccc2)C=Cc2ccccc2C1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.40
MAOA P21397 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
DPP4 P27487 2/20 0.38
HTR2A P28223 3/20 0.33
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PARP1 P09874 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856621 0.75 MAOA (0.36) MAOBMAOACA1CA2PARP1
SCHEMBL6536567 0.74 PARP1 (0.34) MAOBMAOACA1CA2PARP1
SCHEMBL15345381 0.72 HTR2A (0.37) HTR2ACA1CA2PARP1
SCHEMBL3431763 0.72 CYP19A1 (0.31)
SCHEMBL31442138 0.71 HDAC9 (0.35) CA1CA2PARP1HDAC9
SCHEMBL29223962 0.71 CA1 (0.33) CA1CA2PARP1HDAC9
SCHEMBL1725344 0.70 PARP1 (0.36) MAOBHTR2CHTR2BCA1CA2
SCHEMBL7882155 0.70 PARP1 (0.36) MAOBHTR2CHTR2BCA1CA2
SCHEMBL2288761 0.69 PARP1 (0.39) MAOBHTR2CHTR2BCA1CA2
SCHEMBL7729865 0.68 SLC6A2 (0.33) CA1CA2PARP1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657214-A1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL Mitsubishi Gas Chemical Company, Inc. (JP) 2013-10-30 EP disclosed