Dipyridyl

Dipyridyl

SCHEMBL287597

[Ni].c1ccc(-c2ccccn2)nc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.93
LMNA P02545 3/20 0.93
CCR1 P32246 3/20 0.93
CCR5 P51681 3/20 0.93
CCR8 P51685 3/20 0.93
CYP1A2 P05177 1/20 0.93
POLB P06746 1/20 0.93
METAP1 P53582 1/20 0.93
BLM P54132 1/20 0.93
HIF1A Q16665 1/20 0.93
DOHH Q9BU89 1/20 0.93
P4HTM Q9NXG6 1/20 0.93
NPC1 O15118 6/20 0.74
TP53 P04637 4/20 0.74
RAB9A P51151 4/20 0.74
ALOX15 P16050 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL1535115 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7900008 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7904091 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL809478 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL809361 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL286888 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL2207183 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122057585-A Method for recovering activity of deactivated hydrogenation catalyst 中国石油化工股份有限公司 2026-05-19 CN claimed
CN-119954580-A Long chain linear alpha-olefins and process for preparing the same 中国石油天然气股份有限公司 2025-05-09 CN claimed
CN-116966932-A Preparation method of bipyridine nickel-carbon nitride integrated difunctional material 重庆大学 2023-10-31 CN claimed
CN-114959750-B Method for preparing (E) -2, 2-difluoro-4-phenylbut-3-ethyl enoate compound by electrocatalytic 上海第二工业大学 2023-09-01 CN claimed
CN-113684499-B Preparation method and application of nickel-nitrogen co-doped carbon-based catalyst with high metal loading efficiency 大连理工大学 2022-12-02 CN claimed
CN-113684499-A Preparation method and application of nickel-nitrogen co-doped carbon-based catalyst with high metal loading efficiency 大连理工大学 2021-11-23 CN claimed
CN-104402938-B A kind of many acidic group nickel complex composites and preparation method and application 江苏科技大学 2017-04-05 CN claimed
US-7947801-B2 reacting a 9,9-disubstituted-fluorene with an alkyl lithium in the presence of a catalytic amount of a nickel amine complex, to form a poly(9,9-disubstituted-fluorene); fluorescent conjugated polymers useful as blue light-emitting materials THE UNIVERSITY OF MASSACHUSETTS (US) 2011-05-24 US claimed
EP-2295428-A2 Linear pyridazine and pyrrolic compounds, methods of preparation and applications Centre National de la Recherche Scientifique (CNRS) (FR) 2011-03-16 EP claimed
EP-2061785-A2 LINEAR PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2009-05-27 EP claimed
US-20080249282-A1 POLYFLUORENE METHOD MASSACHUSETTS, UNIVERSITY OF 2008-10-09 US claimed
WO-2008012441-A2 LINEAR PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2008-01-31 WO claimed
JP-60228590-A None JP disclosed
JP-56047421-A None JP disclosed
CN-122057585-A Method for recovering activity of deactivated hydrogenation catalyst 中国石油化工股份有限公司 2026-05-19 CN disclosed
US-20260121095-A1 Advanced Ion Exchange Membranes And Applications Thereof WILLIAMS RICHARD KENT (US) 2026-04-30 US disclosed
JP-S60228590-A THIN-FILM ELECTROCHROMIC DISPLAY CELL NIPPON TELEGR & TELEPH CORP <NTT> 1985-11-13 JP disclosed
EP-0125355-A1 Process for the preparation of ZSM-5 or mordenite utilizing transition metal complexes during crystallization MOBIL OIL CORPORATION (US) 1984-11-21 EP disclosed
US-4388285-A TEMPLATES MOBIL OIL CORPORATION (US) 1983-06-14 US disclosed
JP-S5647421-A LINEAR POLY 2,5-THIENYLENE POLYMER, ITS PREPARATION, AND SEMICONDUCTOR COMPRISING IT TOKYO INST OF TECHNOL 1981-04-30 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260121095-A1 Advanced Ion Exchange Membranes And Applications Thereof MYOC, MB, MYOF KDM4E 3825/4885LMNA 32/4885CCR1 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.