SCHEMBL15364016

SCHEMBL15364016

C=C(C)C(=O)OC(O)C#N

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL17668914 0.98 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL13756081 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTHRBTDP1
SCHEMBL33779 0.78 TSHR (0.47) ALDH1A1TSHRTHRBTDP1
SCHEMBL8993196 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL371301 0.75 ALDH1A1 (0.38) ALDH1A1TSHR
Acetic Acid SCHEMBL28158416 0.75 TSHR (0.44) ALDH1A1TSHR
SCHEMBL7124073 0.75 TDP1 (0.44) ALDH1A1TSHRTDP1
Water SCHEMBL10713209 0.75 TSHR (0.46) ALDH1A1TSHRTHRBTDP1
Ethylene SCHEMBL8934253 0.75 TSHR (0.46) ALDH1A1TSHRTHRBTDP1
SCHEMBL3504072 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104245655-B The method for purifying crude acetone stream 利安德化学技术有限公司 2017-06-23 CN disclosed
EP-2844631-B1 METHOD OF PURIFYING CRUDE ACETONE STREAM LYONDELL CHEMICAL TECH LP (US) 2016-12-14 EP disclosed
CN-103030526-B Method for preparing isopropanol by gas phase hydrogenation of acetone CHINA PETROLEUM & CHEMICAL 2015-07-08 CN disclosed
EP-2844631-A1 METHOD OF PURIFYING CRUDE ACETONE STREAM Lyondell Chemical Technology, L.P. (US) 2015-03-11 EP disclosed
CN-104245655-A Method of purifying crude acetone stream LYONDELL CHEMICAL TECH LP 2014-12-24 CN disclosed
US-20130296612-A1 METHOD OF PURIFYING CRUDE ACETONE STREAM LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2013-11-07 US disclosed
WO-2013166130-A1 METHOD OF PURIFYING CRUDE ACETONE STREAM LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2013-11-07 WO disclosed
CN-103030526-A Method for preparing isopropanol by gas phase hydrogenation of acetone CHINA PETROLEUM & CHEMICAL 2013-04-10 CN disclosed