Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.61 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.61 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482229 | 0.98 | CHRNA7 (0.62) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL562670 | 0.98 | CHRNA7 (0.62) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| Hydrochloric Acid SCHEMBL1533941 | 0.96 | CHRNA7 (0.61) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5294019 | 0.92 | HTT (0.62) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL6115421 | 0.91 | CHRNA7 (0.56) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5301421 | 0.90 | HTT (0.66) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5296069 | 0.90 | HTT (0.66) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5286007 | 0.90 | HTT (0.66) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5283392 | 0.90 | HTT (0.66) | CHRNA7CHRNA10CHRNA9HTTMEN1 | |
| SCHEMBL5296041 | 0.90 | HTT (0.66) | CHRNA7CHRNA10CHRNA9HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662332-B1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | NIPPON SODA CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| US-9233849-B2 | Process for producing fluorine-containing sulfonylimide salt | NIPPON SODA CO., LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20130323155-A1 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE SALT | NIPPON SODA CO., LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| EP-2662332-A1 | MANUFACTURING METHOD FOR FLUORINE-CONTAINING SULFONYL IMIDE SALT | Nippon Soda Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |