SCHEMBL15375356

SCHEMBL15375356

CCc1ccccc1OCc1ccccc1C(O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
FABP4 P15090 2/20 0.45
FABP5 Q01469 2/20 0.45
NISCH Q9Y2I1 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTR7 P34969 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
SLC1A5 Q15758 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375521 0.87 RXRA (0.46) MAPTNPSR1FABP4FABP5KDM4E
SCHEMBL15375554 0.87 FABP4 (0.44) L3MBTL1MAPTFABP4FABP5NISCH
SCHEMBL15375597 0.87 CYP2D6 (0.44) MAPTFABP4FABP5KDM4EALDH1A1
SCHEMBL15375287 0.87 FABP4 (0.38) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL15402016 0.86 PTGDR2 (0.50) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL15375388 0.86 FABP4 (0.45) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL15375381 0.84 MAPT (0.45) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL15375564 0.84 RXRA (0.49) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL15402835 0.83 MAPT (0.44) L3MBTL1MAPTNPSR1FABP4FABP5
SCHEMBL8758384 0.83 GABRA1 (0.39) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
CN-102348677-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2012-02-08 CN disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA L3MBTL1 2775/4885MAPT 3967/4885NPSR1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.