Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18435256 | 0.88 | SIGMAR1 (0.46) | TAAR1SIGMAR1SLC18A2MEN1KMT2A | |
| SCHEMBL3829583 | 0.88 | ACE (0.42) | EPHX1ACETAAR1SIGMAR1SLC18A2 | |
| SCHEMBL19559843 | 0.83 | SIGMAR1 (0.53) | EPHX1TAAR1SIGMAR1SLC18A2MEN1 | |
| SCHEMBL7789516 | 0.82 | SIGMAR1 (0.53) | EPHX1TAAR1SIGMAR1SLC18A2MEN1 | |
| SCHEMBL7789508 | 0.80 | EPHX1 (0.61) | EPHX1ACETAAR1SIGMAR1SLC18A2 | |
| SCHEMBL7789504 | 0.80 | EPHX1 (0.61) | EPHX1ACETAAR1SIGMAR1SLC18A2 | |
| SCHEMBL3554246 | 0.79 | CTRB1 (0.50) | ACETAAR1CYP1A2 | |
| SCHEMBL7626858 | 0.79 | CTRB1 (0.50) | ACETAAR1CYP1A2 | |
| SCHEMBL6926559 | 0.78 | SIGMAR1 (0.36) | EPHX1ACETAAR1SIGMAR1MEN1 | |
| SCHEMBL6448643 | 0.76 | TAAR1 (0.41) | EPHX1TAAR1SIGMAR1SLC18A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847242-B1 | CARBINOL-TERMINATED POLYMERS CONTAINING ALLYLAMINE | ARLANXEO DEUTSCHLAND GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-2847242-A1 | CARBINOL-TERMINATED POLYMERS CONTAINING ALLYLAMINE | LANXESS Deutschland GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167410-A1 | CARBINOL-TERMINATED POLYMERS CONTAINING ALLYLAMINE | LANXESS DEUTSCHLAND GMBH (DE) | 2013-11-14 | — | — | WO | disclosed |
| EP-2662392-A1 | Carbinol-terminated polymers containing allylamine | LANXESS Deutschland GmbH (DE) | 2013-11-13 | — | — | EP | disclosed |