Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651960 | 0.84 | ALDH1A1 (0.49) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL3081849 | 0.82 | HCAR2 (0.47) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL24729148 | 0.78 | ALDH1A1 (0.44) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL29009658 | 0.77 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL541750 | 0.77 | HCAR2 (0.51) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL17420660 | 0.76 | ALDH1A1 (0.49) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL8651697 | 0.76 | HCAR2 (0.50) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL28360698 | 0.76 | TSHR (0.40) | ALDH1A1L3MBTL1KMT2ALMNATSHR | |
| SCHEMBL8593724 | 0.75 | HCAR2 (0.41) | HCAR2ALDH1A1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL29837176 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013167585-A2 | RECYCLING OF ORGANOTIN COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2013-11-14 | — | — | WO | disclosed |
| EP-2662379-A1 | Recycling of organotin compounds | Universiteit Antwerpen (BE) | 2013-11-13 | — | — | EP | disclosed |