Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356782 | 0.84 | ALDH1A1 (0.42) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28360686 | 0.83 | CYP3A4 (0.37) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14691956 | 0.81 | C5AR1 (0.40) | TSHRMEN1KMT2AC5AR1ALDH1A1 | |
| SCHEMBL28360720 | 0.80 | KDM4E (0.36) | TSHRMEN1KMT2AC5AR1ALDH1A1 | |
| SCHEMBL28360723 | 0.80 | KDM4E (0.36) | TSHRMEN1KMT2AC5AR1ALDH1A1 | |
| SCHEMBL29009658 | 0.80 | L3MBTL1 (0.38) | TSHRMEN1KMT2AC5AR1ALDH1A1 | |
| SCHEMBL9355639 | 0.79 | TSHR (0.39) | TSHRMEN1KMT2AC5AR1ALDH1A1 | |
| SCHEMBL28357008 | 0.79 | FSCN1 (0.42) | TSHRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28883288 | 0.79 | SMN1; SMN2 (0.39) | TSHRMEN1KMT2ASMN1; SMN2TSPO | |
| SCHEMBL28356849 | 0.79 | ALDH1A1 (0.40) | TSHRMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804008-A | 1, 3-disubstituted indoline derivative and preparation method thereof | 陕西科技大学 | 2020-02-18 | — | — | CN | disclosed |