Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666591 | 0.81 | NOS1 (0.37) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| SCHEMBL27914618 | 0.79 | NOS1 (0.33) | NOS1NOS3NOS2KMT2ALMNA | |
| SCHEMBL4187645 | 0.79 | DGAT1 (0.35) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| SCHEMBL1951895 | 0.78 | DGAT1 (0.39) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| SCHEMBL595785 | 0.78 | DGAT1 (0.39) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| SCHEMBL595786 | 0.78 | DGAT1 (0.39) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL627921 | 0.76 | DGAT1 (0.38) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL627920 | 0.76 | DGAT1 (0.38) | ALDH1A1MAPTPTGS1NOS1NOS3 | |
| SCHEMBL28649428 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL2369655 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTPTGS1NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |