Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911627 | 0.92 | KDM4E (0.52) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL29755650 | 0.92 | KDM4E (0.52) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL3070239 | 0.89 | L3MBTL1 (0.65) | L3MBTL1TDP1MAPTLMNAALDH1A1 | |
| SCHEMBL7904297 | 0.88 | ALDH1A1 (0.50) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL7820909 | 0.88 | ALDH1A1 (0.65) | L3MBTL1TDP1MAPTLMNAALDH1A1 | |
| SCHEMBL10367492 | 0.87 | HTR7 (0.56) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL11727531 | 0.86 | KCNA3 (0.48) | KDM4EL3MBTL1TDP1ALDH1A1KCNA3 | |
| SCHEMBL24838711 | 0.85 | L3MBTL1 (0.38) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL1772752 | 0.85 | ALDH1A1 (0.54) | KDM4EL3MBTL1TDP1MAPTLMNA | |
| SCHEMBL30178764 | 0.85 | L3MBTL1 (0.38) | KDM4EL3MBTL1TDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9716229-B2 | Polymer networks | UNIVERSITY OF HULL (GB) | 2017-07-25 | — | — | US | disclosed |
| EP-2665795-B1 | POLYMER NETWORKS | UNIV HULL (GB) | 2016-05-25 | — | — | EP | disclosed |
| US-20130299805-A1 | POLYMER NETWORKS | UNIVERSITY OF HULL (GB) | 2013-11-14 | — | — | US | disclosed |