Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398937 | 1.00 | CTSK (0.49) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL12592642 | 1.00 | CTSK (0.49) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL21571253 | 0.95 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1411658 | 0.95 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL3004548 | 0.95 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL17688441 | 0.94 | CTSK (0.51) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL690295 | 0.91 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL633418 | 0.91 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL6837916 | 0.87 | CTSK (0.56) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL6745774 | 0.87 | CTSK (0.56) | CTSKCTSSMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190255155-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2019-08-22 | — | — | US | disclosed |
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2019-07-30 | — | — | US | disclosed |
| CN-107208076-A | Butyrylcholine esterase amphoteric ion polymer conjugate | 科达制药 | 2017-09-26 | — | — | CN | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-8846739-B2 | TGR5 agonists | EXELIXIS PATENT COMPANY LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130303505-A1 | TGR5 AGONISTS | EXELIXIS PATENT COMPANY LLC | 2013-11-14 | — | — | US | disclosed |
| CN-102781922-A | TGR5 agonists | EXELIXIS INC | 2012-11-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885MEN1 3310/4885 |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885MEN1 3310/4885 |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885MEN1 3310/4885 |
| US-20190255155-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885MEN1 3310/4885 |
| US-20130303505-A1 | TGR5 AGONISTS | GCGR, NPY5R, TBXA2R | CTSK 3170/4885CTSS 3876/4885MEN1 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.