Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398937 | 0.94 | CTSK (0.49) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL15380893 | 0.94 | CTSK (0.49) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL12592642 | 0.94 | CTSK (0.49) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL21571253 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1411658 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL3004548 | 0.90 | CTSK (0.48) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL633418 | 0.86 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL690295 | 0.86 | CTSK (0.47) | CTSKCTSSMEN1GAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL29801501 | 0.83 | CTSK (0.45) | CTSKCTSSITGB3ITGA2BACE | |
| SCHEMBL6837916 | 0.82 | CTSK (0.56) | CTSKCTSSITGB3ITGA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207128-B1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2022-07-27 | — | — | EP | disclosed |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190255155-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2019-08-22 | — | — | US | disclosed |
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2019-07-30 | — | — | US | disclosed |
| EP-3207128-A2 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| WO-2016061562-A2 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. (US) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10363290-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885ITGB3 731/4885 |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885ITGB3 731/4885 |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885ITGB3 731/4885 |
| US-20190255155-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | CTSK 1996/4885CTSS 1380/4885ITGB3 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.