Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101879 | 0.94 | PTGES (0.47) | KMT2APTGESHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL15380429 | 0.87 | PTGES (0.45) | PTGES | |
| SCHEMBL15380924 | 0.84 | HDAC6 (0.42) | KMT2APTGESSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3094243 | 0.82 | IDH1 (0.44) | KMT2APTGESHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3109449 | 0.82 | PTGES (0.54) | PTGESHPGDALDH1A1KDM4E | |
| SCHEMBL3100803 | 0.82 | PTGES (0.54) | PTGESHPGDALDH1A1KDM4E | |
| SCHEMBL11961904 | 0.82 | PTGES (0.47) | KMT2APTGESHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3111197 | 0.81 | PTGES (0.54) | PTGESHPGDALDH1A1KDM4E | |
| SCHEMBL13393170 | 0.81 | HPGD (0.54) | KMT2APTGESHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11894984 | 0.80 | PTGES (0.47) | KMT2APTGESALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921405-B2 | Compounds | OREXO AB (SE) | 2014-12-30 | — | — | US | disclosed |
| US-20130303571-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303571-A1 | NEW COMPOUNDS | MTX1, LTB4R, RDX | KMT2A 3186/4885PTGES 307/4885HPGD 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.