Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108313 | 0.92 | PTGES (0.43) | HDAC6PTGESKMT2AMEN1CACNA1G | |
| SCHEMBL15380429 | 0.88 | PTGES (0.45) | HDAC6PTGESTP53MAPTPOLB | |
| SCHEMBL3094243 | 0.87 | IDH1 (0.44) | PTGESKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15380913 | 0.84 | KMT2A (0.46) | PTGESKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11894984 | 0.82 | PTGES (0.47) | HDAC6PTGESKMT2AMEN1TP53 | |
| SCHEMBL3100803 | 0.81 | PTGES (0.54) | HDAC6PTGESALDH1A1 | |
| SCHEMBL3109449 | 0.81 | PTGES (0.54) | HDAC6PTGESALDH1A1 | |
| SCHEMBL3112010 | 0.81 | PTGES (0.44) | HDAC6PTGESKMT2AMEN1TP53 | |
| SCHEMBL3094236 | 0.80 | PTGES (0.45) | PTGESKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3099237 | 0.80 | PTGES (0.46) | PTGESKMT2AMEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921405-B2 | Compounds | OREXO AB (SE) | 2014-12-30 | — | — | US | disclosed |
| US-20130303571-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303571-A1 | NEW COMPOUNDS | MTX1, LTB4R, RDX | HDAC6 460/4885PTGES 307/4885KMT2A 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.